How a Single Cell Sense its Mechanical Environment?

How a Single Cell Sense its Mechanical Environment?

How Do Bone Cells Sense Mechanical Loading?

Influenced by gravidity, bone tissue experiences stronger or lighter deformation according to the strength of the activities of daily life. Activities resulting in impact are particularly known to stimulate osteogenesis, thus reducing bone mass loss. Knowing how bone cells recognize the mechanical deformation imposed to the bone and trigger a series of biochemical chain reactions is of crucial ...

A sense of self-worth: energy taxis provides insight into how Helicobacter pylori navigates through its environment.

The ability to perceive and respond appropriately to environmental cues is an essential prerequisite to the survival and adaptation of microorganisms to changes in their surroundings. One of the best-understood responses involves the chemotaxis two-component signal transduction system in Escherichia coli, which functions to relay sensory information about the surroundings to the flagellar motil...

Periodic flexible maintenance planning in a single-machine production environment

Preventive maintenance is the essential part of many maintenance plans. From the production point of view, the flexibility of the maintenance intervals enhances the manufacturing efficiency. On the contrary, the maintenance departments tend to know the timing of the long term maintenance plans as certain as possible. In a single-machine production environment, this paper proposes a simulation–o...

How Does a Single Cell Know When the Liver Has Reached Its Correct Size?

The liver is a multi-functional organ that regulates major physiological processes and that possesses a remarkable regeneration capacity. After loss of functional liver mass the liver grows back to its original, individual size through hepatocyte proliferation and apoptosis. How does a single hepatocyte 'know' when the organ has grown to its final size? This work considers the initial growth ph...